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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CANX
All Species:
25.15
Human Site:
Y514
Identified Species:
36.89
UniProt:
P27824
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27824
NP_001019820.1
592
67568
Y514
K
Q
T
S
G
M
E
Y
K
K
T
D
A
P
Q
Chimpanzee
Pan troglodytes
XP_001151304
592
67554
Y514
K
Q
T
S
A
M
E
Y
K
K
T
D
A
P
Q
Rhesus Macaque
Macaca mulatta
XP_001101429
592
67582
Y514
K
Q
T
S
A
M
E
Y
K
K
T
D
A
P
Q
Dog
Lupus familis
XP_533285
610
69806
S503
V
K
K
K
Y
E
D
S
E
Y
K
K
T
D
I
Cat
Felis silvestris
Mouse
Mus musculus
P35564
591
67259
Y515
K
Q
S
N
A
M
E
Y
K
K
T
D
A
P
Q
Rat
Rattus norvegicus
P35565
591
67236
Y515
K
Q
S
N
A
M
E
Y
K
K
T
D
A
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506871
598
67609
Y517
K
Q
P
S
A
A
E
Y
K
K
T
D
A
P
Q
Chicken
Gallus gallus
NP_001025791
599
68090
Y515
K
Q
P
S
A
A
E
Y
K
K
T
D
A
P
Q
Frog
Xenopus laevis
NP_001080326
611
69964
H526
K
Q
P
L
D
A
E
H
K
K
T
D
A
P
Q
Zebra Danio
Brachydanio rerio
NP_998613
600
67856
A522
K
S
S
A
S
T
P
A
A
K
Y
K
K
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29413
406
46790
M356
T
Q
A
G
E
K
K
M
K
E
A
Q
D
E
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34652
619
69189
A512
S
K
P
T
P
N
F
A
K
K
S
D
A
Y
S
Sea Urchin
Strong. purpuratus
XP_791226
591
66512
K509
P
E
E
Y
E
V
K
K
R
D
G
A
T
P
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9SP22
420
47921
K370
A
A
F
D
E
A
E
K
K
K
E
E
E
D
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P29402
530
60468
E460
T
E
L
I
E
K
A
E
Q
Q
P
N
L
T
I
Baker's Yeast
Sacchar. cerevisiae
P27825
502
56949
R444
G
S
D
G
P
T
E
R
K
F
M
N
S
R
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98.6
59.1
N.A.
93
93.5
N.A.
85.7
82.8
78.2
70.8
N.A.
31.7
N.A.
40.5
53.7
Protein Similarity:
100
99.8
99.4
75.2
N.A.
96.6
97.4
N.A.
93.1
90.8
86.2
84.1
N.A.
44.7
N.A.
58.9
69.7
P-Site Identity:
100
93.3
93.3
0
N.A.
80
80
N.A.
80
80
66.6
13.3
N.A.
13.3
N.A.
26.6
6.6
P-Site Similarity:
100
93.3
93.3
20
N.A.
93.3
93.3
N.A.
80
80
73.3
26.6
N.A.
26.6
N.A.
46.6
33.3
Percent
Protein Identity:
N.A.
29.3
N.A.
40
25.6
N.A.
Protein Similarity:
N.A.
44.4
N.A.
53.5
41.2
N.A.
P-Site Identity:
N.A.
20
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
7
38
25
7
13
7
0
7
7
57
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
7
7
0
7
0
0
7
0
57
7
13
13
% D
% Glu:
0
13
7
0
25
7
63
7
7
7
7
7
7
7
0
% E
% Phe:
0
0
7
0
0
0
7
0
0
7
0
0
0
0
0
% F
% Gly:
7
0
0
13
7
0
0
0
0
0
7
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
13
% I
% Lys:
57
13
7
7
0
13
13
13
75
69
7
13
7
0
0
% K
% Leu:
0
0
7
7
0
0
0
0
0
0
0
0
7
0
7
% L
% Met:
0
0
0
0
0
32
0
7
0
0
7
0
0
0
0
% M
% Asn:
0
0
0
13
0
7
0
0
0
0
0
13
0
0
0
% N
% Pro:
7
0
25
0
13
0
7
0
0
0
7
0
0
57
0
% P
% Gln:
0
57
0
0
0
0
0
0
7
7
0
7
0
0
50
% Q
% Arg:
0
0
0
0
0
0
0
7
7
0
0
0
0
7
0
% R
% Ser:
7
13
19
32
7
0
0
7
0
0
7
0
7
0
7
% S
% Thr:
13
0
19
7
0
13
0
0
0
0
50
0
13
13
0
% T
% Val:
7
0
0
0
0
7
0
0
0
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
7
0
0
44
0
7
7
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _